CARMAweb performs data preprocessing background correction, quality control and normalization , detection of differentially expressed genes, cluster analysis, dimension reduction and visualization, classification, and Gene Ontology-term analysis. This web application accepts raw data from a variety of imaging software tools for the most widely used microarray platforms:
This practical is conceived as an overview of a microarray data analysis process. Its goal is not to provide an in-deep understanding of each step but rather a "taste" of the process.
September 14, ; Accepted date: October 24, ; Published date:
It is intuitively clear that true biological signal and confounding factors need to be simultaneously considered when performing normalization. However, the most popular normalization approaches do not utilize what is known about the study, both in terms of the biological variables of interest and the known technical factors in the study, such as batch or array processing date.
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